|
Symbol Name ID |
Hsd17b4
hydroxysteroid (17-beta) dehydrogenase 4 MGI:105089 |
| * | Aspects of the system are reported to show a normal phenotype. |
| Darker colors indicate more annotations |
| Human Phenotypes | Hypergonadotropic hypogonadism |
Hypoplasia of the ovary |
Streak ovary |
Bicornuate uterus |
Hypoplasia of the uterus |
Gonadal dysgenesis |
Premature ovarian insufficiency |
Amenorrhea |
Primary amenorrhea |
Secondary amenorrhea |
Oligomenorrhea |
| Disease(s) Associated with HSD17B4 | |||||||||||
| Perrault syndrome |
| Mouse Phenotypes | reproductive system phenotype |
abnormal male germ cell morphology |
abnormal spermatid morphology |
abnormal seminal vesicle morphology |
abnormal testis morphology |
abnormal seminiferous tubule morphology |
seminiferous tubule degeneration |
small testis |
small uterus |
abnormal gametogenesis |
abnormal spermatogenesis |
abnormal male reproductive system morphology |
abnormal epididymis morphology |
reduced female fertility |
decreased litter size |
male infertility |
reduced male fertility |
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| Availability | Mouse Genotype | |||||||||||||||||
| Hsd17b4em1(IMPC)Tcp/Hsd17b4em1(IMPC)Tcp | ||||||||||||||||||
| Hsd17b4tm1Baes/Hsd17b4tm1Baes | ||||||||||||||||||
| Hsd17b4em1(IMPC)Tcp/Hsd17b4+ | ||||||||||||||||||
| Hsd17b4tm2Baes/Hsd17b4tm2Baes Cnptm1(cre)Kan/Cnp+ (conditional) |
* | |||||||||||||||||
| Hsd17b4tm2Baes/Hsd17b4tm2Baes Tg(Nes-cre)1Kln/0 (conditional) |
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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO) |
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last database update 04/16/2024 MGI 6.23 |
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